Methods for evaluating drug-resistance gene expression in the cancer patient
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United States of America Patent
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Aug 3, 2010
Grant Date -
Aug 7, 2003
app pub date -
Nov 19, 2002
filing date -
Nov 20, 2001
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Abstract
The methods of the invention detect in a qualitative or quantitative fashion drug-resistance RNA and DNA in blood plasma, serum, and other bodily fluids. The methods of the invention thereby enable the assessment of drug resistance in a neoplasm without the requirement of a tissue biopsy. The inventive methods are useful for the evaluation, monitoring, and selecting of drug treatment regimens, and for determining a predisposition for or prognosis of chemoresistant neoplastic disease.
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