Intramolecularly cross-linked hemoglobin and method of preparation
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United States of America Patent
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Apr 22, 1986
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N/A
app pub date -
Mar 29, 1985
filing date -
Mar 29, 1985
priority date (Note) -
Expired
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Abstract
Stroma-free hemoglobin cross-linked with reagents that mimic 2,3 diphosphoglycerate and transform stroma-free hemoglobin into a physiologically competent oxygen carrier which is retained in vivo for adequate periods of time and thus can be used in fluids for transporting oxygen; reagents for cross-linking stroma-free hemoglobin and method for cross-linking stroma-free hemoglobin.
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