Methods and devices for endovascular ablation of a splanchnic nerve

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United States of America Patent

PATENT NO 11751939
APP PUB NO 20210128229A1
SERIAL NO

16963559

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Abstract

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Systems, devices, and methods for transvascular ablation of target tissue are disclosed herein. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are method of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

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Patent Owner(s)

Patent OwnerAddress
AXON THERAPIES INC2326 WALSH AVENUE SANTA CLARA CA 95051

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Engelman, Zoar Jacob New York, US 21 861
Gelfand, Mark New York, US 302 31237
Leung, Mark S Duncan, CA 39 3046
Panescu, Dorin San Jose, US 259 40615
Wu, Andrew Los Altos Hills, US 83 10411

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