Apparatus and method for protecting neurons and reducing inflammation and scarring

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11911504
APP PUB NO 20210052491A1
SERIAL NO

16966683

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A device for protecting neurons and reducing inflammation and adhesion formation following surgery is provided. Also provided is a method for protecting neurons and reducing inflammation and adhesion formation following surgery. The device includes a bioabsorbable substrate and a layer of an oxidation inhibitor mimicking the effects of superoxide dismutase and catalase enzymes located on a surface of the substrate. Oxidation inhibitors that may be used include EUK-8, EUK-134, EUK-189, and EUK-207 (a mimetic of superoxide dismutase/catalase), monosodium luminol or phenyl N-t-butylnitrone or an analog with similar anti-oxidant properties. The oxidation inhibitors reduce oxidative stress and trigger the subject's natural anti-oxidant and anti-inflammatory defenses, thereby reducing neuron death, loss of neuron connectivity, inflammation and scarring and restoring excitatory function of neurons.

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Patent Owner(s)

  • GALEN THERAPEUTICS LLC

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Toker, Tunc Boston, US 2 0

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