Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
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United States of America Patent
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Oct 6, 2009
Grant Date -
Jan 23, 2003
app pub date -
Jul 19, 2002
filing date -
Jul 23, 2001
priority date (Note) -
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Abstract
A method and apparatus for physiological modulation, including neural and gastrointestinal modulation, for the purposes of treating several disorders, including obesity, depression, epilepsy, and diabetes. The method and apparatus includes chronically implanted neural and neuromuscular modulators, used to modulate the afferent neurons of the sympathetic nervous system to induce satiety. Furthermore, the method and apparatus includes neuromuscular stimulation of the stomach to effect baseline and intermittent smooth muscle contraction to increase gastric intraluminal pressure, which induces satiety, and stimulates sympathetic afferent fibers, including those in the sympathetic trunk, splanchnic nerves, and greater curvature of the stomach, to augment the perception of satiety.
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