4-substituent-2-hydroxylmorpholine-3-one and preparation method thereof

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United States of America Patent

PATENT NO 9676736
APP PUB NO 20150087828A1
SERIAL NO

14394041

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Abstract

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A molecule with neural activities, especially 4-substituent-2-hydroxymorpholin-3-one, as a new intermediate of neurokinin-1 receptor antagonist aprepitant, and preparation method thereof.

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Patent Owner(s)

  • SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY;ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cai, Qingfeng Zhejiang, CN 4 8
Chai, Jian Zhejiang, CN 9 1
Liu, Chonghao Shanghai, CN 2 0
Qiu, Pengcheng Shanghai, CN 4 1
Zhang, Fuli Shanghai, CN 11 4

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