Dual cytokine fusion proteins comprising IL-10

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United States of America Patent

PATENT NO 11613563
APP PUB NO 20220275039A1
SERIAL NO

17684151

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Abstract

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The application relates to a dual cytokine fusion protein composition, pharmaceutical composition, and/or formulation thereof comprising IL-10 or IL-10 variant molecules fused to a single chain variable fragment scaffolding system and a second cytokine, where the second cytokine is linked in the hinge region of the scFv. The application also relates to methods of using the dual cytokine fusion protein composition for treating cancer, inflammatory diseases or disorders, and immune and immune mediated diseases or disorders.

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Patent Owner(s)

Patent OwnerAddress
DEKA BIOSCIENCES INC20271 GOLDENROD LN SUITE 2087 GERMANTOWN MD 20876

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mumm, John Germantown, US 37 111

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