Tethered ligands and methods of use
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United States of America Patent
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Mar 2, 2004
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N/A
app pub date -
Nov 24, 2000
filing date -
Dec 20, 1999
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Abstract
The invention provides methods, reagents and devices for analysis of receptor ligand interactions, determining the profile of receptor expression in cells and cell populations, and diagnostic and drug screening methods. The invention makes use of immobilized tethered ligand fusion proteins having a ligand domain, a stalk domain, and optionally an immobilization domain.
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