Method for diagnosing and assessing endometriosis

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11965879
APP PUB NO 20210123910A1
SERIAL NO

16999851

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Abstract

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A method of detecting the expression level of miRNA markers in a biological sample obtained from a mammal is provided. The method incudes the steps of i) detecting the expression level of one or more miRNA markers selected from the group of miR-199a-3p, miR-143-3p, miR-340-5p, let-7b-5p, miR-21-5p, miR-17-5p, miR-20a-5p and miR-103a-3p, in the biological sample; ii) detecting the expression level of at least one miRNA reference marker selected from miR-148b-3p and miR-30e-5p in the biological sample; and iii) normalizing the expression level of the miRNA marker(s) against the expression level of the miRNA reference marker in the sample and in a control. The method is useful for the diagnosis of endometriosis, monitoring of patient response to treatment, and assessment of disease progression and/or severity.

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Patent Owner(s)

  • MCMASTER UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Foster, Warren G Hamilton, CA 2 20

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