1-Phenacyl-3-phenyl-3-(piperidylethyl)piperidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them

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United States of America Patent

PATENT NO 6642233
SERIAL NO

09913106

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to the compounds of formula: ##STR1## as well as to the salts thereof with inorganic or organic acids, to solvates thereof and/or to hydrates thereof, which have strong affinity and high selectivity for the human NK.sub.1 receptors of substance P. The invention also relates to the process for preparing them, to the intermediate compounds of formula (VII) which are useful for the preparation, to pharmaceutical compositions containing them and to their fuse for the manufacture of medicinal products intended for treating any pathology in which substance P and the human NK.sub.1 receptors are involved.

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Patent Owner(s)

Patent OwnerAddress
SANOFI-AVENTIS174 AVENUE DE FRANCE PARIS 75013

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ducoux, Jean-Philippe Combaillaux, FR 13 28
Emonds-Alt, Xavier Combaillaux, FR 50 510
Gueule, Patrick Teyran, FR 33 263
Proietto, Vincenzo Saint Georges D'Orques, FR 50 547

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