Human voltage gated sodium channel .beta.1A subunit and methods of use

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United States of America Patent

PATENT NO 7408036
APP PUB NO 20060269996A1
SERIAL NO

11370490

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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DNAs encoding human voltage gated sodium channel .beta.1A subunit have been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been expressed in recombinant host cells that produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.

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Patent Owner(s)

  • ORTHO-MCNEIL PHARMACEUTICAL, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Codd, Ellen Blue Bell, PA 18 47
D'Andrea, Michael Cherry Hill, NJ 177 132
Qin, Ning Blue Bell, PA 29 126

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