Therapies for B cell malignancies

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11976118
APP PUB NO 20230009888A1
SERIAL NO

17371770

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The subject invention provides novel methods for treating B cell malignancies, such as multiple myeloma, using a combination therapy. Said treatment in accordance with the subject invention comprises the administration of a B cell regulator, e.g., a galectin molecule, to a subject suffering from a B cell malignancy, and wherein said subject received, receives, or will receive a treatment with a conventional treatment for such B cell malignancy, e.g., immunotherapy. The administration of the galectin molecule boosts the expression of B cell specific antigens e.g., SLAMF7, on MM cells, thereby increasing the sensitivity of MM cells to anti-SLAMF7 Ab and therapeutic efficacy of Elotuzumab.

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Patent Owner(s)

  • THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dimitroff, Charles J Coral Gables, US 8 7

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