Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses
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United States of America Patent
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Sep 21, 2010
Grant Date -
Dec 23, 2004
app pub date -
Nov 25, 2002
filing date -
Nov 26, 2001
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Expired
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Abstract
This invention related to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed In a variety of dementias, and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson′s disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to compounds useful for treatment of such conditions and methods of using these compounds for such treatment.
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