Method for determination of absolute configuration of chiral compounds
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United States of America Patent
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Jun 15, 2010
Grant Date -
Jul 6, 2006
app pub date -
Feb 6, 2004
filing date -
Feb 6, 2003
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Abstract
The present invention provides a simple, highly sensitive, and highly precise method for determining the absolute configuration of a chiral compound such as a diamine or an amino alcohol.The present invention is directed to a method for determining the absolute configuration of an asymmetric carbon of a chiral compound on the basis of the sign of the Cotton effect by analyzing a solution containing the chiral compound and a porphyrin dimer by circular dichroism spectroscopy.
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