Medicinal compositions improving brain function and method for improving brain function
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United States of America Patent
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Mar 11, 2008
Grant Date -
Nov 10, 2005
app pub date -
Apr 3, 2003
filing date -
Jun 14, 2002
priority date (Note) -
In Force
status (Latency Note)
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Abstract
An alkyl ether derivative represented by the formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, m and n are as defined in the specification, or salts thereof exhibits synergistically improved anti-hypoxic activity when combined with a compound having an acetylcholine esterase inhibitory activity. Therefore, the combination according to the present invention is useful as a method for improving cerebral function. Further, a pharmaceutical composition containing the compound relating to the combination according to the present invention is useful for treatment and prevention of dysfunction of cerebral acetylcholine neurons in the sequelae of cerebrovascular dementia, senile dementia, Alzheimer's disease and ischemic cerebral lesion and in the cerebral apoplexy or the memory impairment caused by selective neuronal death.
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