Adenine DNA base editor variants with reduced off-target RNA editing

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United States of America Patent

PATENT NO 11946040
APP PUB NO 20200308571A1
SERIAL NO

16781979

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Abstract

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Engineered adenine base editor (ABE) variants with reduced RNA editing activity, and methods of using the same.

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Patent Owner(s)

  • THE GENERAL HOSPITAL CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Grunewald, Julian Charlestown, US 6 7
Joung, J Keith Winchester, US 102 2651
Zhou, Ronghao Charlestown, US 4 4

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