Genetically encoded calcium indicators and methods of use

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United States of America Patent

PATENT NO 11572401
APP PUB NO 20190153067A1
SERIAL NO

16198166

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Abstract

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Genetically encoded calcium indicator (GECI) polypeptides and the nucleic acid molecules encoding such polypeptides are provided. In addition, methods of using such nucleic acids and polypeptides in methods of screening for agonists or antagonists of G-protein coupled receptor (GPCR) or ion channels and methods of monitoring neural activity also are provided.

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Patent Owner(s)

  • HOWARD HUGHES MEDICAL INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Douglas Reston, US 13 90
Looger, Loren Sterling, US 21 103
Schreiter, Eric Ashburn, US 7 37
Svoboda, Karel Leesburg, US 12 57

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