Monoclonal antibodies that bind to the V3 loop of HIV-1 gp120

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United States of America Patent

PATENT NO 8722861
APP PUB NO 20110044995A1
SERIAL NO

12743442

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Abstract

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The present invention provides a monoclonal antibody that recognizes the V3 loop of the envelope glycoprotein gp120 of AIDS virus, which is any one selected from the following antibodies:

    (a) an antibody having the amino acid sequence shown in SEQ ID NO: 1 as the amino acid sequence of a H chain variable region (VH), and having the amino acid sequence shown in SEQ ID NO: 2 as the amino acid sequence of a L chain variable region (VL); and(b) an antibody having the amino acid sequence shown in SEQ ID NO: 3 as the amino acid sequence of a H chain variable region (VH), and having the amino acid sequence shown in SEQ ID NO: 4 as the amino acid sequence of a L chain variable region (VL).

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Patent Owner(s)

  • KUMAMOTO UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsushita, Shuzo Kumamoto, JP 18 221
Yoshimura, Kazuhisa Kumamoto, JP 14 25

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