Genes encoding key catalyzing mechanisms for ethanol production from syngas fermentation

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United States of America Patent

PATENT NO 9284538
APP PUB NO 20140206054A1
SERIAL NO

14083007

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Abstract

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Gene sequences of key acetogenic clostridial species were sequenced and isolated. Genes of interest were identified, and functionality was established. Key genes of interest for metabolic catalyzing activity in clostridial species include a three-gene operon coding for CODH activity, a two-gene operon coding for PTA-ACK, and a novel acetyl coenzyme A reductase. The promoter regions of the two operons and the acetyl coA reductase are manipulated to increase ethanol production.

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Patent Owner(s)

  • COSKATA, INC.;SYNATA BIO, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Datta, Rathin Chicago, US 62 1050
Reeves, Andrew Chicago, US 30 287

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