Method and system for producing high purity vancomycin hydrochloride

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United States of America Patent

PATENT NO 9428291
APP PUB NO 20140260098A1
SERIAL NO

14024131

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Abstract

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A method is provided for preparing spray dried powder containing vancomycin hydrochloride. The method comprises providing a vancomycin hydrochloride solution with a chromatographic purity of at least 95%, adding an excipient to the vancomycin hydrochloride solution to form a mixture solution of the vancomycin hydrochloride solution and the excipient, concentrating the mixed solution of the vancomycin hydrochloride solution and the excipient to form a 20% to 30% vancomycin concentrate, filtering the vancomycin concentrate to form a final filtrate, and spray drying the final filtrate to form a spray dried vancomycin hydrochloride powder with EP impurity B level of not more than 1.5%.

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Patent Owner(s)

Patent OwnerAddress
ZHEJIANG MEDICINE CO LTD168 MID ZHIYUAN AVENUE BINHAI NEW AREA SHAOXING CITY 312500

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sun, Xianqiang Xinchang Zhejiang, CN 2 0
Teo, Choon Hangahou Zhejliang, CN 3 7
Wang, Xiaoyong Shaoxing, Zhejiang, CN 165 1162

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