Compositions, devices and methods for multi-stage release of chemotherapeutics
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United States of America Patent
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Jun 13, 2023
Grant Date -
Mar 25, 2021
app pub date -
Dec 2, 2020
filing date -
Dec 29, 2014
priority date (Note) -
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Abstract
In one aspect, the present disclosure provides microparticles that are configured to release a first drug over a first time period and to release a second drug over a second time period, wherein a lag period of substantially no drug release occurs between the first and second time periods. In other aspects, the present disclosure pertains to the use of such microparticles in delivery systems and methods of treatment. In another aspect, the present disclosure pertains to drug delivery systems that comprising a folded inflatable drug delivery balloon that comprises folds and microparticles positioned within the folds.
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