Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease
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United States of America Patent
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Sep 18, 2007
Grant Date -
Feb 3, 2005
app pub date -
Jun 10, 2004
filing date -
Jun 10, 2003
priority date (Note) -
Expired
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Abstract
Disclosed herein are carbonyl compounds of Formula I, II, or III, and others as described herein. ##STR00001## Also disclosed are methods of treating disease, such as cancer, neurological disorders, including polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, autoimmune diseases and cardiovascular conditions, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.
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