Process for binding IgG to protein A

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United States of America Patent

PATENT NO 4704366
SERIAL NO

06623797

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Abstract

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Unusually strong binding of IgG to protein A is achieved by contacting these components in the presence of a medium containing a high concentration of salt. Although such binding is of general utility, a particularly useful application is the purification of monoclonal antibodies from ascites fluid by affinity chromatography.

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Patent Owner(s)

  • BIO-RAD LABORATORIES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Juarez-Salinas, Hector Larkspur, CA 3 57
Ott, Gary S Livermore, CA 22 486

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