Antibiotic polymers
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United States of America Patent
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Jul 8, 2008
Grant Date -
May 12, 2005
app pub date -
Aug 6, 2004
filing date -
Feb 7, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Polymers (i.e. polyesters, polyamides, polythioesters, polyanhydrides, or a mixture thereof) which degrade hydrolytically to provide a combination of a beta-lactam antibiotic (e.g., amoxicillin) and a beta-lactamase inhibitor (e.g., clavulanic acid) (or a pharmaceutically acceptable salt thereof) are provided. Methods of producing these polymers, intermediates useful for preparing these polymers, and methods of using these polymers to deliver a combination of a beta-lactam antibiotic and a beta-lactamase inhibitor (or a pharmaceutically acceptable salt thereof) to a host are also provided.
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