Internalizing anti-CD74 antibodies and methods of use

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United States of America Patent

PATENT NO 7919087
APP PUB NO 20080138333A1
SERIAL NO

11754902

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis.

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Patent Owner(s)

  • IMMUNOMEDICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goldenberg, David M Morris Plains, US 517 13204
Hansen, Hans J Morris Plains, US 224 5649
Leung, Shui-on Morris Plains, US 46 1853
Qu, Zhengxing New Jersey, US 88 2625

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