Nucleic acid sequencing using affinity reagents

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United States of America Patent

PATENT NO 11788138
APP PUB NO 20210254150A1
SERIAL NO

17084482

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Abstract

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The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.

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Patent Owner(s)

  • MGI TECH CO., LTD.; BGI-SHENZHEN CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Callow, Matthew J Redwood City, US 38 2245
Drmanac, Radoje Los Altos Hills, US 132 5981
Drmanac, Snezana Los Altos Hills, US 57 3922
Eckhardt, Leon Soquel, US 4 4
Li, Handong San Jose, US 63 574
Xu, Xun Shenzhen, CN 84 473
Yang, Naibo Burlingame, US 8 4

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