Method of modifying bone resorption with .DELTA.9(11)-dehydro-8-isoestrone
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United States of America Patent
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Mar 5, 1996
Issued Date -
N/A
app pub date -
Dec 1, 1994
filing date -
Apr 8, 1994
priority date (Note) -
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Abstract
This invention relates to 8.alpha.-3-hydroxyestra-1,3,5(10),9(11)tetraen-17-one (.DELTA.9(11)-dehydro-8-isoestrone) (VI), ##STR1## to the process for its preparation, to pharmaceutical compositions containing said 8.alpha.-3-hydroxyestra-1,3,5(10),9(11)tetraen-17-one (.DELTA.9(11)-dehydro-8-isoestrone) (VI) and to the use of said 8.alpha.-3-hydroxyestra-1,3,5(10),9(11)tetraen-17-one (.DELTA.9(11)-dehydro-8-isoestrone) (VI) for modifying the balance between bone production and bone resorption, and as an antioxidant in a host animal, including man.
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