System and method for leakage control in a particle capture system

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United States of America Patent

PATENT NO 11814671
APP PUB NO 20210164023A1
SERIAL NO

17170576

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Abstract

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A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.

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Patent Owner(s)

Patent OwnerAddress
BIO-RAD LABORATORIES INC1000 ALFRED NOBEL DRIVE HERCULES CA 94547

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deol, Yadwinder Ann Arbor, US 5 9
Handique, Kalyan Ann Arbor, US 224 14268
Sharma, Vishal Ann Arbor, US 86 1419
Stark, John Ann Arbor, US 26 161

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