Peyer's patch and/or M-cell targeting ligands
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United States of America Patent
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Jul 12, 2005
Grant Date -
May 22, 2003
app pub date -
Jun 28, 2002
filing date -
Jul 2, 2001
priority date (Note) -
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Abstract
Purified synthetic polypeptide ligands comprising a 12-mer L-peptide, D-peptides being the D-form of the 12-mer L-peptides, 12-mer retro-inverted peptides being the retro-inverted form of the 12-mer L-peptide, or fragments and homologues thereof, are disclosed. These ligands are for targeting pharmaceutical agents and carriers comprising such agents to intestinal epithelial tissue, especially Peyer's patch and/or M-Cell tissue. Methods of using the ligands are also disclosed.
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