Test apparatus and methods for ST2 cardiac biomarker

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United States of America Patent

PATENT NO 11525828
SERIAL NO

16441400

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Abstract

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The technology described in this document can be embodied in a test strip for use in measuring a level of an ST2 cardiac biomarker in a blood plasma sample. The test strip includes a base, and a plurality of conjugates, wherein each conjugate includes a reporter group bound to a first antibody that binds to ST2. A conjugate pad disposed along a length of the base and is configured to hold the plurality of conjugates that bind with ST2 to produce conjugate-ST2 complexes. The conjugate pad is further configured to receive the blood plasma sample. The test strip also includes a plurality of second and third antibodies that bind to ST2, and the conjugate-ST2 complexes, respectively. The plurality of second antibodies are bound to a membrane in a test location and the plurality of third antibodies are bound to the membrane in a control location.

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Patent Owner(s)

  • CRITICAL CARE DIAGNOSTICS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bender, Jillian Elizabeth Carlsbad, US 5 33
Chung, Roy A Carlsbad, US 10 240
Kuo, Shrin P Carlsbad, US 5 33
Snider, James V San Diego, US 51 1121

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