Oligonucleotide probe for detecting single nucleotide polymorphisms, and method for determining cis-trans configuration

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United States of America Patent

PATENT NO 11851701
APP PUB NO 20210040544A1
SERIAL NO

16980367

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Abstract

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A probe comprising a reporter region for detecting a first single nucleotide polymorphism, an anchor region for detecting a second single nucleotide polymorphism, and a linker region is disclosed. The reporter region comprises an oligonucleotide consisting of a sequence perfectly matching with the first target sequence, and a fluorescent dye that quenches when hybridized to the first target sequence where the first single nucleotide polymorphism is present. The anchor region comprises an oligonucleotide consisting of a sequence perfectly matching with a second target sequence where the second single nucleotide polymorphism is present. A length of the oligonucleotide of the reporter region is shorter than a length of the oligonucleotide of the anchor region.

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Patent Owner(s)

Patent OwnerAddress
EIKEN KAGAKU KABUSHIKI KAISHATOKYO 110-8480

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Matsui, Atsuka Tochigi, JP 2 0

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