Template imprinted materials by RFGD plasma deposition
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United States of America Patent
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Oct 17, 2000
Grant Date -
N/A
app pub date -
Apr 15, 1999
filing date -
Apr 17, 1998
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Template-imprinted structures 10 are provided having at least one template-imprinted surface 12 defining indentations 14 that are capable of specifically binding cells and/or molecules, such as macromolecules including proteins, peptides and nucleic acids. Presently preferred embodiments of the template-imprinted structures include medical prostheses, such as artificial joints and heart valves, having surface indentations that specifically bind proteins and/or cells that enhance the biocompatibility of the prosthesis, thereby making it less likely that the prosthesis will be rejected by the body. Methods are also provided for making the template-imprinted structures of the present invention.
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