Aroylethenylpiperidinobutyrophenone antipsychotic agents
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United States of America Patent
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Aug 11, 1981
Grant Date -
N/A
app pub date -
Sep 4, 1979
filing date -
Sep 4, 1979
priority date (Note) -
Expired
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Abstract
4-Aroylethnyl-1-piperidinobutyrophenone derivatives and pharmaceutically acceptable salts thereof of the following general structure: ##STR1## wherein R is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl; and R' is hydrogen or halogen, are useful as antipsychotic agents. The novel compounds are produced by aldol condensation of an acetophenone with a protected 4-(4-formyl-1-piperidino)-butyrophenone.
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