Cell culture array system for automated assays and methods of operation and manufacture thereof

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United States of America Patent

PATENT NO 9376658
SERIAL NO

12348907

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Abstract

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A number of novel improved microfluidic configurations and systems and methods of manufacture and operation. In one embodiment, three wells are used for independent cell culture systems in a cell culture array. In a second aspect, artificial sinusoids with artificial epithelial barriers are provided with just one (optionally shared or multiplexed) fluidic inlet and one (optionally shared or multiplexed) fluidic output, where the medium output also functions as a cellular input. A pneumatic cell loader combined with other components provides a fully automated cell culture system. Magnetic alignment of plate molds provides advantages and ease of molded manufacture.

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Patent Owner(s)

  • EMD MILLIPORE CORPORATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hung, Paul J Berkeley, US 10 301
Lee, Philip J Alameda, US 17 495

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