5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use as anti-inflammatory agents
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United States of America Patent
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Sep 3, 1985
Grant Date -
N/A
app pub date -
Jul 5, 1983
filing date -
Aug 20, 1982
priority date (Note) -
Expired
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Abstract
The present invention relates to novel 5-oxo-5H-[1]benzopyrano[2,3-b]pyridine derivatives useful for effective medicines for the treatment of various connective tissue diseases such as chronic rheumatoid arthritis and varieties of inflammatory diseases caused by immunoreaction, which have the following formula: ##STR1## wherein R is the same or different and represents hydrogen, alkyl, alkoxy, nitro, hydroxyl, acyl, hydroxyalkyl, halogen with the proviso that m is 1,2 or 3, or a tetramethylene (--(CH.sub.2).sub.4 --) or butadienylene (--CH.dbd.CH--CH.dbd.CH--) group which, in conjunction with two adjacent carbon atoms on the ring, forms a six-membered ring with the proviso that m is 1; n is 1 or 2, or a physiologically acceptable salt or ester thereof.
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