Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders

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United States of America Patent

PATENT NO 11872311
APP PUB NO 20200222321A1
SERIAL NO

16800855

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Abstract

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Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILLCAMPUS BOX 4105 308 BYNUM HALL CHAPEL HILL NC 27599

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Della, Rocca Joseph Blue Bell, US 4 55
Kramer, Stephanie Johnson City, US 2 10
Lin, Wenbin Chicago, US 40 256
Liu, Demin Round Lake, US 9 79
Poon, Christopher Y Carlsbad, US 3 55

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