Vector for expression of polypeptides in bacilli

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United States of America Patent

PATENT NO 4801537
SERIAL NO

06717800

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Abstract

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A replicable plasmidic expression vector, capable of high levels of expression and secretion of polypeptides in a bacillus is disclosed. The vector contains a DNA sequence comprising the promoter and regulatory regions which control expression and secretion of proteases in a bacillus operably liked to a DNA sequence encoding the amino acid sequence of a polypeptide. The expression vector is particularly useful in the production of B. amyloliquefaciens proteases or other heterologous proteins in B. subtilis.

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Patent Owner(s)

  • ENZON, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banner, Carl D B Bethesda, MD 1 16
Nagarajan, Vasantha Rockville, MD 79 3245
Rhodes, Craig S Washington, DC 2 16

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