Replication competent hepatitis C virus and methods of use
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United States of America Patent
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Oct 30, 2007
Grant Date -
Jul 14, 2005
app pub date -
Dec 6, 2004
filing date -
Dec 23, 1999
priority date (Note) -
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Abstract
The present invention provides a replication competent hepatitis C virus that includes a heterologous polynucleotide. The invention also includes methods for modifying a hepatitis C virus polynucleotide, selecting a replication competent hepatitis C virus polynucleotide, detecting a replication competent hepatitis C virus polynucleotide, and identifying a compound that inhibits replication of a hepatitis C virus polynucleotide.
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