Photoimmunotherapies for cancer using combination therapies
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United States of America Patent
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Mar 3, 2009
Grant Date -
Dec 26, 2002
app pub date -
May 1, 2002
filing date -
May 1, 2001
priority date (Note) -
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Abstract
The present invention relates to photosensitizer immunoconjugate compositions and combination therapies for use in cancer related photodynamic treatments and diagnostic methods. Photosensitizer immunoconjugates comprising a photosensitizer conjugated to a tumor-specific and/or tumoricidial antibody and processes for the preparation thereof are described. The use of photosensitizer immunoconjugates (PICs) offers improved photosensitizer delivery specificity for diagnostic and therapeutic applications. Combination therapies to co-localize activated photosensitizer compounds and tumoricidal antibodies in tumor tissues are also described.
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