Retrocyclins: antiviral and antimicrobial peptides
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United States of America Patent
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Mar 30, 2004
Grant Date -
Jul 31, 2003
app pub date -
May 6, 2002
filing date -
Apr 18, 2001
priority date (Note) -
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Abstract
Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
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