Intermediate in the production of adrenergic blocking agents

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United States of America Patent

PATENT NO 4247710
SERIAL NO

06073051

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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There are disclosed compounds of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n --wherein n is 2 to 20, ##STR2## R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy, and ##STR3## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n --wherein n is 2 to 20, ##STR4## and R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy and racemates thereof. There are also disclosed processes and intermediate utilized to produce the end products. The end products have utility as agents exhibiting both .alpha. and selective .beta. adrenergic blocking action.

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Patent Owner(s)

  • HOFFMANN-LA ROCHE INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fahrenholtz, Kenneth E Bloomfield, NJ 10 34
Guthrie, Robert W Saddle Brook, NJ 25 223
Kierstead, Richard W North Caldwell, NJ 27 212
Tilley, Jefferson W North Caldwell, NJ 33 282

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