Morphogen treatments for limiting proliferation of epithelial cells

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United States of America Patent

PATENT NO 6399569
SERIAL NO

08461113

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are methods and compositions for maintaining the integrity of the gastrointestinal tract luminal lining in a mammal, including (1) limiting epithelial cell proliferation, (2) inhibiting ulcerative lesion formation, (3) inhibiting inflammation normally associated with ulcerative diseases, and (4) stimulating the repair of ulcerative lesions and the regeneration of the luminal tissue. The methods and compositions include a therapeutically effective amount of a morphogen as defined herein.

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Patent Owner(s)

  • MARIEL THERAPEUTICS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Charette, Marc F Needham, MA 18 335
Cohen, Charles M Medway, MA 55 908
Kuberasampath, Thangavel Medway, MA 76 2452
Oppermann, Hermann Medway, MA 112 3788
Ozkaynak, Engin Milford, MA 58 1378
Pang, Roy H L Etna, NH 50 1091
Rueger, David C Hopkinton, MA 109 3083
Smart, John E Weston, MA 32 405

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