Composition and method for reducing joint pain associated with hemarthrosis and hemophilic arthropathy

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 11793762
APP PUB NO 20200352869A1
SERIAL NO

16940759

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Abstract

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The invention disclosed herein relates to a composition and method of reducing the joint pain associated with hemarthrosis or hemophilic arthropathy. The method includes administering a COX-2 inhibitor, such as rofecoxib, celecoxib, valdecoxib, etoricoxib or other “coxib” drug which is encapsulated in PLGA micro-particles. The COX-2 inhibitor can be administered directly to an area where pain exists by an injection device. In a preferred embodiment, rofecoxib or celecoxib can be encapsulated in PLGA micro-particles for controlled, sustained release over a 2-8-week period. The non-systemic delivery and the controlled, sustained release of rofecoxib alleviate the cardiovascular side effects associated with systemic rofecoxib treatments.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Battogtokh, Gantumur Incheon, KR 3 0
Gotov, Oyuntuya Incheon, KR 3 0
Hahn, Soonkap Irvine, US 22 1119
Kim, Gil Man Anyang, KR 3 0
Seo, Min Hyo Daejeon, KR 39 365

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