Naphthyridine derivatives
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United States of America Patent
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Jan 27, 1998
Grant Date -
N/A
app pub date -
Mar 24, 1997
filing date -
Oct 6, 1994
priority date (Note) -
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Abstract
Compounds of formula (I) including pharmaceutically acceptable salts thereof in which R.sub.1 represents a C.sub.1-6 alkyl group; R.sub.2 represents a group of the formula COOR.sub.4 in which R.sub.4 represents a C.sub.1-5 alkyl group; and R.sub.3 represents a group of formula COOR.sub.5 in which R.sub.5 represents a C.sub.1-5 alkyl group are disclosed, which are anti-rheumatic agents and are useful as modulators of cytokine synthesis, immunomodulatory agents, anti-inflammatory agents and anti-allergic agents. Compositions containing these compounds and processes to make these compounds are also disclosed.
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