Fungal alpha-amylase variants
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United States of America Patent
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Feb 22, 2011
Grant Date -
Jun 3, 2010
app pub date -
Feb 2, 2010
filing date -
Aug 22, 2003
priority date (Note) -
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Abstract
The inventors have developed a method of altering the amino acid sequence of a fungal alpha-amylase to obtain variants, and they have used the method to construct such variants. The variants may be useful for anti-staling in baked products. Accordingly, the invention provides a method of constructing fungal alpha-amylase variants based on a comparison of three-dimensional (3D) structures of the fungal alpha-amylase and a maltogenic alpha-amylase. One or both models includes a substrate. The invention also provides novel fungal alpha-amylase variants.
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