Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors

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United States of America

PATENT NO 11319324
APP PUB NO 20210317128A1
SERIAL NO

16759262

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Abstract

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The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

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Patent Owner(s)

  • BAYER AKTIENGESELLSCHAFT; BAYER PHARMA AKTIENGESELLSCHAFT

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bräuer, Nico Falkensee, DE 17 14
Carr, James Lindsay Abingdon, GB 9 5
Connelly, Ursinyova Nina Abingdon, GB 1 0
Davenport, Adam James Abingdon, GB 20 9
Fischer, Oliver Martin Berlin, DE 15 22
Koppitz, Marcus Berlin, DE 55 100
Nagel, Jens Daxweiler, DE 52 1839
Neuhaus, Roland Berlin, DE 41 160
Parrott, Shelley Anne Abingdon, GB 7 2
Pook, Elisabeth Wuppertal, DE 38 195
Rotgeri, Andrea Berlin, DE 40 255
Siebeneicher, Holger Berlin, DE 25 106
Townsend, Robert James Abingdon, GB 5 17

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