Intra-droplet surface engineering to capture a molecular target

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United States of America Patent

PATENT NO 11181521
APP PUB NO 20190113509A1
SERIAL NO

16091217

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Abstract

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The present invention relates to a method for capturing a molecular target present in the aqueous phase of a water-in-oil emulsion, said method being based on the use of a binding system comprising (a) a surfactant bearing a functional moiety on its hydrophilic head group and (b) a chemoprobe that acts as a molecular staple between the functionalized surfactant and the molecular target and comprises at least two distinct domains namely (i) at least one capture moiety which is able to specifically bind the molecular target and (ii) at least one binding domain which is able to interact with the functional group of the surfactant through covalent or non-covalent interactions, directly or through a binding intermediary.

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Patent Owner(s)

  • UNIVERSITE DE STRASBOURG; CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS); CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIÈRES DE LA CHIMIE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Griffiths, Andrew David Paris, FR 72 6960
Pernod, Ketty Gries, FR 2 0
Ryckelynck, Michael Strasbourg, FR 3 264
Ursuegui, Sylvain Strasbourg, FR 6 2
Wagner, Alain Strasbourg, FR 27 57

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