GASP1: a follistatin domain containing protein
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United States of America Patent
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Mar 20, 2007
Grant Date -
Aug 28, 2003
app pub date -
Feb 21, 2003
filing date -
Feb 21, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to the use of a protein, GASP1, comprising at least one follistatin domain to modulate the level or activity of growth and differentiation factor-8 (GDF-8). More particularly, the invention relates to the use of GASP1 for treating disorders that are related to modulation of the level or activity of GDF-8. The invention is useful for treating muscular diseases and disorders, particularly those in which an increase in muscle tissue would be therapeutically beneficial. The invention is also useful for treating diseases and disorders related to metabolism, adipose tissue, and bone degeneration.
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