Antibodies directed to angiopoietin-2 and uses thereof
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United States of America Patent
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Jul 5, 2011
Grant Date -
Nov 2, 2006
app pub date -
Dec 19, 2005
filing date -
Dec 21, 2004
priority date (Note) -
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Abstract
Antibodies directed to the antigen Ang-2 and uses of such antibodies are described. In particular, fully human monoclonal antibodies directed to the antigen Ang-2. Nucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3. Hybridomas or other cell lines expressing such immunoglobulin molecules and monoclonal antibodies.
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