Therapeutic musk antibodies

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United States of America Patent

PATENT NO 11492401
APP PUB NO 20220259304A1
SERIAL NO

17565994

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Abstract

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The present invention relates to antibody-based molecules, including full-length antibodies, antigen-binding domains thereof, and antibody derivatives that are capable of binding to and activating human muscle-specific tyrosine protein kinase (MuSK). The present invention further discloses methods of treating neuromuscular conditions using the aforementioned MuSK antibodies.

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Patent Owner(s)

  • MOUNT SINAI OF MEDICINE OF NEW YORK UNIVERSITY; ARGENX IIP BV

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blanchetot, Christophe Ghent, BE 34 106
Burden, Steven J New York, US 6 2
Koide, Akiko New York, US 30 113
Koide, Shohei New York, US 123 1292
Leloup, Nadia New York, US 2 0
Oury, Julien New York, US 2 0
Silence, Karen Ghent, BE 51 645
Vanhauwaert, Roeland Ghent, BE 3 0

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